The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2016

Filed:

Jan. 09, 2014
Applicant:

Niigata University, Niigata, JP;

Inventors:

Takayoshi Shimohata, Niigata, JP;

Lawrence M. Kauvar, San Francisco, CA (US);

Assignee:

NIIGATA UNIVERSITY, Niigata, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/37 (2006.01); A61K 38/49 (2006.01); C07D 231/12 (2006.01); C07D 233/56 (2006.01); A61K 45/06 (2006.01); A61K 39/395 (2006.01); C07K 16/22 (2006.01); A61K 38/17 (2006.01); A61K 38/18 (2006.01); A61K 31/277 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 31/277 (2013.01); A61K 38/177 (2013.01); A61K 38/1866 (2013.01); A61K 38/49 (2013.01); A61K 45/06 (2013.01); C07K 16/22 (2013.01); A61K 2039/505 (2013.01); A61K 2300/00 (2013.01);
Abstract

Methods and pharmaceutical compositions for treating severe ischemic events including cerebral infarction, cardiac infarction, or pulmonary embolism, comprising a thrombolytic intervention including thrombolytic agents and an inhibitor of vascular endothelial growth factor (VEGF) receptor-mediated signal transduction are disclosed.


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