The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2016

Filed:

Aug. 22, 2014
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

Mohamed Abazeed, Cleveland, OH (US);

Matthew Meyerson, Concord, MA (US);

Drew Adams, Cambridge, MA (US);

Assignees:

The Broad Institute, Inc., Cambridge, MA (US);

Dana-Farher Cancer Institute, Inc., Cambridge, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/00 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01); A61K 31/5377 (2006.01); A61N 5/10 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61N 5/10 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); A61N 2005/1098 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The invention provides for the use of radiation sensitizing agents in combination with radiation for the treatment of neoplasia, methods for the identification of genotype-specific radiation sensitizing agents, and methods of identifying patients who could benefit from therapy with a genotype-specific radiation sensitizing agent.


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