The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2016

Filed:

Nov. 01, 2012
Applicant:

Synta Pharmaceuticals Corp., Lexington, MA (US);

Inventor:

David Proia, Newton, MA (US);

Assignee:

Synta Pharmaceuticals Corp., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61K 31/05 (2006.01); A61K 31/353 (2006.01); A61K 45/06 (2006.01); A61K 31/4196 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 31/05 (2013.01); A61K 31/353 (2013.01); A61K 31/4196 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01);
Abstract

A pharmaceutical combination comprising a topoisomerase I inhibitor, and an Hsp90 inhibitor according to the following formulae (I) (Ia) a tautomer, or a pharmaceutically acceptable salt thereof, wherein the variables in the structural formulae are defined herein. Also provided is a method for treating a proliferative disorder in a subject in need thereof, using the pharmaceutical combination described herein.


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