The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2016

Filed:

Jul. 13, 2015
Applicant:

Prometic Biosciences, Inc., Laval, Quebec, CA;

Inventors:

Lyne Gagnon, Laval, CA;

Brigitte Grouix, Laval, CA;

Lilianne Geerts, Saint-Lazare, CA;

Pierre Laurin, Ville Mont-Royal, CA;

Christopher Penney, Pierrefonds, CA;

Boulos Zacharie, Laval, CA;

Assignee:

PROMETIC BIOSCIENCES INC., Quebéc, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 27/00 (2006.01); A61K 31/015 (2006.01); A61K 31/192 (2006.01); A61K 31/196 (2006.01); A61K 31/22 (2006.01); A61K 31/513 (2006.01); A61K 31/675 (2006.01); A61K 31/7068 (2006.01); C07C 57/46 (2006.01); C07C 57/48 (2006.01); C07C 59/54 (2006.01); C07C 59/84 (2006.01); C07C 62/20 (2006.01); C07C 229/18 (2006.01); C07C 229/42 (2006.01); C07C 323/52 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 31/196 (2013.01); A61K 31/22 (2013.01); A61K 31/513 (2013.01); A61K 31/675 (2013.01); A61K 31/7068 (2013.01); C07C 57/46 (2013.01); C07C 57/48 (2013.01); C07C 59/54 (2013.01); C07C 59/84 (2013.01); C07C 62/20 (2013.01); C07C 229/18 (2013.01); C07C 229/42 (2013.01); C07C 323/52 (2013.01);
Abstract

New uses for phenylketone carboxylate compounds and substituted aromatic compounds of Formula I, Formula I.1, Formula I.2, Formula IA, Formula IB, Formula IC and Formula II and their pharmaceutical acceptable salts for the treatment of cancer. The use of a combination of two of these compounds is described and the use of the combination of one of these compounds with an anticancer agent such as decarbazine, doxorubicin, daunorubicin, cyclophosphamide, busulfex, busulfan, vinblastine, vincristine, bleomycin, etoposide, topotecan, irinotecan, taxotere, taxol, 5-fluorouracil, methotrexate, gemcitabine, cisplatin, carboplatin and chlorambucil.


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