The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2016

Filed:

Aug. 14, 2013
Applicants:

Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada, Reno, NV (US);

Stc.unm, Albuquerque, NM (US);

Regents of the University of Minnesota, St. Paul, MN (US);

Inventors:

Thomas Kozel, Reno, NV (US);

William Murphy, Reno, NV (US);

Suzanne Brandt, Boise, ID (US);

Bruce R Blazar, Golden Valley, MN (US);

Julie A Lovchik, Albuquerque, NM (US);

Peter Thorkildson, Reno, NV (US);

Ann Percival, Reno, NV (US);

C. Rick Lyons, Ft. Collins, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); A61K 39/07 (2006.01); A01K 39/02 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56911 (2013.01); A61K 39/07 (2013.01); G01N 2333/32 (2013.01);
Abstract

Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals againstor other capsulated pathogens. The methods include administering a capsular polypeptide of a pathogen of interest and a CD40 agonist to a human or animal. The capsular polypeptide or the CD40 agonist is administered in such an amount or frequency that an immunoprotective response can be elicited in the human or animal against the pathogen of interest. In another aspect, the present invention provides methods of using passive immunization with anti-capsular polypeptide antibodies to prevent or treat infections caused byor other pathogens. In yet another aspect, the present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum or other biological samples.


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