The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2016

Filed:

Jan. 09, 2013
Applicant:

Tecan Trading Ag, Mannedorf, CH;

Inventors:

S. Nicholas Reimitz, Campbell, CA (US);

Bruce Richardson, Los Gatos, CA (US);

Marc N. Feiglin, East Brunswick, NJ (US);

Anne R. Kopf-Sill, Portola Valley, CA (US);

Assignee:

Tecan Trading AG, Mannedorf, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
G01N 27/44782 (2013.01); B01L 3/502738 (2013.01); B01L 3/502792 (2013.01); B01L 3/5029 (2013.01); B01L 3/502715 (2013.01); B01L 3/523 (2013.01); B01L 3/527 (2013.01); B01L 7/52 (2013.01); B01L 2200/025 (2013.01); B01L 2200/027 (2013.01); B01L 2200/04 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/141 (2013.01); B01L 2300/044 (2013.01); B01L 2300/0672 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/089 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/161 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0427 (2013.01); B01L 2400/0478 (2013.01); B01L 2400/0683 (2013.01);
Abstract

A cartridge manipulates samples in liquid droplets with an electrode array when a working film is placed on the array. The cartridge has a body with lower surface and wells to hold samples, each with a bottom opening to release liquid. A piercable bottom structure seals the bottom openings. A working film below the body has a hydrophobic upper surface. A peripheral spacer connects the working film to the body and forms a gap is between the body and surface. A top piercing system located in at least one of the wells has a piston and a piercing element, the piston being movable in the well and the piercing element piercing the piercable bottom structure for releasing a sample from a well into the gap.


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