The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2016

Filed:

Dec. 22, 2006
Applicants:

John I. Glass, Germantown, MD (US);

Lei Young, Gaithersburg, MD (US);

Carole Lartigue, Gaithersburg, MD (US);

Nacyra Assad-garcia, Germantown, MD (US);

Hamilton O. Smith, Reistertown, MD (US);

Clyde A. Hutchison, La Jolla, CA (US);

J. Craig Venter, Alexandria, VA (US);

Inventors:

John I. Glass, Germantown, MD (US);

Lei Young, Gaithersburg, MD (US);

Carole Lartigue, Gaithersburg, MD (US);

Nacyra Assad-Garcia, Germantown, MD (US);

Hamilton O. Smith, Reistertown, MD (US);

Clyde A. Hutchison, La Jolla, CA (US);

J. Craig Venter, Alexandria, VA (US);

Assignee:

Synthetic Genomics, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); C12N 15/63 (2006.01); C12N 15/10 (2006.01); C12R 1/35 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C12N 2510/00 (2013.01);
Abstract

A method is provided for introducing a genome into a cell or cell-like system. The introduced genome may occur in nature, be manmade with or without automation, or may be a hybrid of naturally occurring and manmade materials. The genome is obtained outside of a cell with minimal damage. Materials such as a proteins, RNAs, polycations, nucleoid condensation proteins, or gene translation systems may accompany the genome. The genome is installed into a naturally occurring cell or into a manmade cell-like system. A cell-like system or synthetic cell resulting from the practice of the provided method may be designed and used to yield gene-expression products, such as desired proteins. By enabling the synthesis of cells or cell-like systems comprising a wide variety of genomes, accompanying materials and membrane types, the provided method makes possible a broader field of experimentation and bioengineering than has been available using prior art methods.


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