The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2016
Filed:
Jul. 29, 2014
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
John J. Rossi, Azusa, CA (US);
Dongho Kim, Beverly Hills, CA (US);
Patric Lundberg, Rancho Cucamonga, CA (US);
Edouard Cantin, Alhambra, CA (US);
Assignee:
CITY OF HOPE, Duarte, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01); C12N 15/117 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/117 (2013.01); C12N 15/1131 (2013.01); C12N 2310/14 (2013.01); C12N 2310/17 (2013.01); C12N 2310/18 (2013.01); C12N 2310/53 (2013.01); C12N 2320/30 (2013.01); C12N 2330/30 (2013.01);
Abstract
Double-stranded and single-stranded RNA molecules, and their use in methods for inducing interferon are provided. The interferon induction provides anti-viral and other medically useful effects, such as anti-cancer effects. Also provided are methods for reducing or inhibiting interferon induction exhibited by such molecules, particularly siRNA and shRNA molecules produced in vitro.