The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9434949 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 06, 2016

Filed:

Aug. 16, 2011
Applicants:

Yueqiong Cao, Shanghai, CN;

Dalong LV, Shanghai, CN;

Xiangying Zhu, Shanghai, CN;

Haixiong Han, Shanghai, CN;

Honghua Qu, Shanghai, CN;

Yangsheng Jin, Shanghai, CN;

Inventors:

Yueqiong Cao, Shanghai, CN;

Dalong Lv, Shanghai, CN;

Xiangying Zhu, Shanghai, CN;

Haixiong Han, Shanghai, CN;

Honghua Qu, Shanghai, CN;

Yangsheng Jin, Shanghai, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/113 (2010.01); A61K 45/06 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 45/06 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2740/15043 (2013.01);
Abstract

The present invention discloses uses of the human ZFX gene and drugs associated therewith. Also disclosed are uses of the human ZFX gene in tumor treatment, tumor diagnosis, and drug preparation. Further disclosed are small interfering RNA (siRNA), and nucleic acid and lentivirus encoding the siRNA to the human ZFX gene and uses thereof. The siRNA and nucleic acid and lentivirus encoding the siRNA provided by the present invention can specifically inhibit the expression of human ZFX gene. Lentiviruses in particular can efficiently infect target cells, inhibit ZFX expression in target cells, and inhibit the growth of tumor cells, thus promote tumor apoptosis and have great significance in tumor treatment.


Find Patent Forward Citations

Cao, Yueqiong. (2016). Uses of the human zfx gene and drugs associated with same (U.S. Patent No. 9434949). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9434949

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