The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2016
Filed:
Jul. 12, 2013
Applicant:
Zedira Gmbh, Darmstadt, DE;
Inventors:
Christian Buchold, Bad Vilbel, DE;
Uwe Gerlach, Bad Vilbel, DE;
Martin Hils, Darmstadt, DE;
Ralf Pasternack, Griesheim, DE;
Johannes Weber, Darmstadt, DE;
Assignee:
ZEDIRA GMBH, Darmstadt, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); C07K 5/093 (2006.01); A61K 38/07 (2006.01); C07K 1/06 (2006.01); C07K 5/113 (2006.01); A61K 38/06 (2006.01); C07K 5/10 (2006.01); C07D 213/75 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 493/10 (2006.01); C07D 401/06 (2006.01); C07K 5/02 (2006.01); C07K 5/083 (2006.01); C07K 5/117 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1021 (2013.01); A61K 38/06 (2013.01); A61K 38/07 (2013.01); A61K 45/06 (2013.01); C07D 213/75 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 493/10 (2013.01); C07K 1/068 (2013.01); C07K 5/0202 (2013.01); C07K 5/081 (2013.01); C07K 5/0819 (2013.01); C07K 5/1002 (2013.01); C07K 5/1024 (2013.01);
Abstract
The invention relates to pyridinone derivatives of general formula (I) as inhibitors of tissue transglutaminase, to methods for producing the pyridinone derivatives, to pharmaceutical compositions containing said pyridinone derivatives and to their use for the prophylaxis and treatment of diseases associated with tissue transglutaminase.