IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9434743 B1

PDFFull Text
Date of Patent:
Sep. 06, 2016

Filed:

Feb. 28, 2013

Indazole derivatives

Applicant:

Takeda Pharmaceutical Company Limited, San Diego, CA (US);

Inventors:

Zacharia Cheruvallath, San Diego, CA (US);

Philip Erickson, San Diego, CA (US);

Jun Feng, San Diego, CA (US);

Mallareddy Komandla, San Diego, CA (US);

John David Lawson, San Diego, CA (US);

Christopher McBride, San Diego, CA (US);

Joanne Miura, San Diego, CA (US);

Sean Murphy, San Diego, CA (US);

Mingnam Tang, San Diego, CA (US);

Huong-Thu Ton-Nu, San Diego, CA (US);

Assignee:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Attorney:

Matthew J. Russo

Primary Examiner:

Kamal Saeed

Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 401/04 (2006.01); C07D 471/04 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 417/04 (2006.01); C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 231/56 (2006.01); C07D 403/10 (2006.01); C07D 407/14 (2006.01); C07D 413/04 (2006.01); C07D 413/10 (2006.01); A61K 31/416 (2006.01); A61K 31/4245 (2006.01); A61K 31/427 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/506 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/5383 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61K 31/416 (2013.01); A61K 31/427 (2013.01); A61K 31/4245 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/506 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/5383 (2013.01); A61K 45/06 (2013.01); C07D 231/56 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 405/04 (2013.01); C07D 407/14 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R, R, R, R, R, and Rare defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating obesity and related diseases, disorders, and conditions associated with MetAP2.

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