The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2016
Filed:
Dec. 12, 2013
Applicants:
Dainippon Sumitomo Pharma Co., Ltd., Osaka-shi, JP;
Kyowa Hakko Bio Co., Ltd., Tokyo, JP;
Inventors:
Masaji Kasai, Takaoka, JP;
Shinji Kita, Takaoka, JP;
Tadashi Ogawa, Takaoka, JP;
Hideaki Tokai, Takaoka, JP;
Assignees:
Sumitomo Dainippon Pharma Co., Ltd., Osaka, JP;
Kyowa Hakko Bio Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/20 (2006.01); C07C 271/22 (2006.01); C07D 207/416 (2006.01); C12P 7/62 (2006.01); C12P 17/10 (2006.01); C12P 41/00 (2006.01); C12P 17/18 (2006.01);
U.S. Cl.
CPC ...
C07D 487/20 (2013.01); C07C 271/22 (2013.01); C07D 207/416 (2013.01); C12P 7/62 (2013.01); C12P 17/10 (2013.01); C12P 17/182 (2013.01); C12P 41/005 (2013.01); C07B 2200/07 (2013.01);
Abstract
Provided is a process for producing (3R)-2'-(4-bromo-2-fluorobenzyl)spiro{pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine}-1′,2,3′,5(2′H)-tetraone (compound A). The method includes converting an optically active succinimide derivative of formula (I) to compound A, in which the compound of formula (I) has been prepared by reacting a base with an optically active amide derivative of formula (VI).