The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2016
Filed:
Feb. 08, 2013
Zhejiang Hisun Pharmaceutical Co., Ltd., Zhejiang, CN;
Shanghai Institute of Pharmaceutical Industry, Shanghai, CN;
Fuli Zhang, Shangai, CN;
Chunbo Yang, Shangai, CN;
Bin Liang, Shangai, CN;
Pengcheng Qiu, Shangai, CN;
Hairong Luo, Zhejiang, CN;
Jiang Li, Zhejiang, CN;
Jian Chai, Zhejiang, CN;
Qingfeng Cai, Zhejiang, CN;
Abstract
Disclosed is a new method for preparing a methyl substitute of a linezolid intermediate, (S)-2-(3-(3-fluoro-4-morpholinophenyl)-2-oxo-5-oxazoline) (I), wherein the intermediate (I) is obtained by the cyclization of 3-fluoro-4-morpholinophenyl isocyanate (II) and epoxy compound (III). This process has a short process route, low cost, easy operation, and high yield, so is suitable for a large-scale industrial production.