The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2016
Filed:
Mar. 09, 2015
Applicant:
Celgene Corporation, Summit, NJ (US);
Inventors:
Terrence J. Connolly, Warick, NY (US);
Alexander L. Ruchelman, Cream Ridge, NJ (US);
Kelvin H. Y. Yong, Westfield, NJ (US);
Chengmin Zhang, Florham Park, NJ (US);
Assignee:
Celgene Corporation, Summit, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 315/04 (2006.01); C07D 209/49 (2006.01); C07D 209/48 (2006.01); C07D 209/46 (2006.01);
U.S. Cl.
CPC ...
C07D 209/48 (2013.01); C07C 315/04 (2013.01); C07D 209/46 (2013.01); C07D 209/49 (2013.01); C07B 2200/05 (2013.01);
Abstract
Processes for the preparation of certain isoindole compounds, and isotopologues thereof, are provided. In some embodiments, the processes comprise catalytic asymmetrical hydrogenation with hydrogen gas or deuterium gas in a solvent containing exchangeable proton or deuterium for proton-deuterium exchange.