The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2016

Filed:

Nov. 15, 2012
Applicants:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

Rashid Bashir, Champaign, IL (US);

Eric Salm, Champaign, IL (US);

Carlos Eduardo Duarte Guevara, Urbana, IL (US);

Muhammad Ashraf Alam, West Lafayette, IN (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); B01L 7/00 (2006.01); H05B 6/80 (2006.01); H05B 3/00 (2006.01);
U.S. Cl.
CPC ...
B01L 7/52 (2013.01); C12Q 1/686 (2013.01); H05B 3/00 (2013.01); H05B 6/802 (2013.01);
Abstract

Provided herein are methods and devices for rapidly and accurately heating fluid droplets surrounded by a gas-phase medium, such as air. Sub-nanoliter fluid droplets can be rapidly heated by nanoscale field effect transistors via microwave heating by an applied AC voltage to the FET. The heating is in a well-defined interior portion of the fluid droplet, with minimal heating of the outer portion of the fluid droplet, thereby minimizing evaporation. In this manner, rapid thermal cycling is possible, including independently and in parallel for a plurality of droplets. Accordingly, the methods and devices provided herein are used in point-of-care detection such as by PCR that is high speed, robust and of low cost.


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