The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2016
Filed:
Feb. 18, 2011
Ashok Arasappan, Bridgewater, NJ (US);
F. George Njoroge, Carmel, IN (US);
Cecil D. Kwong, Homewood, AL (US);
Subramaniam Ananthan, Birmingham, AL (US);
Frank Bennett, Cranford, NJ (US);
Francisco Velazquez, Clinton, NJ (US);
Vinay M. Girijavallabhan, Denville, NJ (US);
Yuhua Huang, Westfield, NJ (US);
Hollis S. Kezar, Iii, Hoover, AL (US);
Joseph A. Maddry, Birmingham, AL (US);
Robert C. Reynolds, Birmingham, AL (US);
Abhijit Roychowdhury, Homewood, AL (US);
Anita T. Fowler, Irondale, AL (US);
John A. Secrist, Iii, Birmingham, AL (US);
Joseph A. Kozlowski, Princeton, NJ (US);
Bandarpalle B. Shankar, Branchburg, NJ (US);
Ling Tong, Warren, NJ (US);
Seong Heon Kim, Livingston, NJ (US);
Malcolm Maccoss, Seabrook Island, SC (US);
Srikanth Venkatraman, Edison, NJ (US);
Vishal Verma, Jersey City, NJ (US);
Ashok Arasappan, Bridgewater, NJ (US);
F. George Njoroge, Carmel, IN (US);
Cecil D. Kwong, Homewood, AL (US);
Subramaniam Ananthan, Birmingham, AL (US);
Frank Bennett, Cranford, NJ (US);
Francisco Velazquez, Clinton, NJ (US);
Vinay M. Girijavallabhan, Denville, NJ (US);
Yuhua Huang, Westfield, NJ (US);
Hollis S. Kezar, III, Hoover, AL (US);
Joseph A. Maddry, Birmingham, AL (US);
Robert C. Reynolds, Birmingham, AL (US);
Abhijit Roychowdhury, Homewood, AL (US);
Anita T. Fowler, Irondale, AL (US);
John A. Secrist, III, Birmingham, AL (US);
Joseph A. Kozlowski, Princeton, NJ (US);
Bandarpalle B. Shankar, Branchburg, NJ (US);
Ling Tong, Warren, NJ (US);
Seong Heon Kim, Livingston, NJ (US);
Malcolm MacCoss, Seabrook Island, SC (US);
Srikanth Venkatraman, Edison, NJ (US);
Vishal Verma, Jersey City, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Southern Research Institute, Birmingham, AL (US);
Abstract
The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R, X, Y, Z, R, R, R, R, R, R, R, R, R, Rand n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.