The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2016

Filed:

Feb. 10, 2016
Applicant:

Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);

Inventors:

Adam D. Hughes, Half Moon Bay, CA (US);

Erik Fenster, San Bruno, CA (US);

Melissa Fleury, Brisbane, CA (US);

Anne-Marie Beausoleil, San Mateo, CA (US);

Venkat R. Thalladi, Foster City, CA (US);

Jerry Nzerem, South San Francisco, CA (US);

Miroslav Rapta, San Carlos, CA (US);

Assignee:

Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/216 (2006.01); A61K 9/08 (2006.01); C07C 231/24 (2006.01); C07C 231/12 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); C07C 235/74 (2006.01); C07C 231/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/216 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 45/06 (2013.01); C07C 231/12 (2013.01); C07C 231/14 (2013.01); C07C 231/24 (2013.01); C07C 235/74 (2013.01); C07B 2200/07 (2013.01); C07B 2200/13 (2013.01);
Abstract

In one aspect, the invention relates to a compound of the structure: or a pharmaceutically acceptable salt thereof, and a crystalline form of this compound, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this compound; methods of using this compound; and processes for preparing this compound.


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