The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Oct. 16, 2013
Bristol-myers Squibb Company, Princeton, NJ (US);
Allison Y. Luo, East Hanover, NJ (US);
Wendy L. Trigona, Newtown, PA (US);
Jinshan Shen, Skillman, NJ (US);
Li-An Xu, Branchburg, NJ (US);
Yan Zhang, Princeton, NJ (US);
Bruce Stouffer, Branchburg, NJ (US);
Haibin Chen, San Jose, CA (US);
Haichun Huang, Fremont, CA (US);
Xiaolu Tao, Hopewell, NJ (US);
Catherine Brockus, Princeton, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
In certain embodiments, the present invention provides a method of treating an Interferon gamma inducible protein 10 (IP-10)-related disease in a subject, comprising: (a) administering to the subject a predetermined dosage of an anti-IP-10 antibody; (b) detecting the level of the anti-IP-10 antibody in a sample of the subject; and (c) if the level of the anti-IP-10 antibody from step (b) is below a threshold exposure level, increasing the dosage of the anti-IP-10 antibody in the subject such that the IP-10 related disease in the subject is treated. In certain embodiments, the present invention provides an isolated monoclonal anti-idiotypic antibody, or an antigen binding portion thereof, which binds to the anti-IP-10 antibody MDX-1100.