The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2016

Filed:

Nov. 05, 2015
Applicant:

Postech Academy-industry Foundation, Gyeongsangbuk-do, KR;

Inventors:

Changill Ban, Gyeongsangbuk-do, KR;

Yoon-Keun Kim, Seoul, KR;

Hunho Jo, Busan, KR;

Seonghwan Lee, Gyeonggi-do, KR;

Hyung Jun Youn, Seoul, KR;

Assignee:

Postech Academy-Industry Foundation, Gyeongsangbuk-do, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); G01N 33/574 (2006.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
G01N 33/57434 (2013.01); C12N 15/115 (2013.01); C12N 2310/16 (2013.01); G01N 2333/47 (2013.01);
Abstract

The present invention relates to a DNA aptamer specifically binding to EN2 (Engrailed-2), a biosensor for diagnosing prostate cancer having the same, and a method of diagnosing prostate cancer. A strong binding force and excellent specificity of the DNA aptamer of the present invention and the biosensor using the same with respect to EN2 proteins were identified. A detection specificity problem of a prostate-specific antigen (PSA) test used for prostate cancer diagnosis of the related art was addressed. Therefore, the present invention is expected to be beneficially used for early diagnosis of prostate cancer more effectively and increase diagnostic accuracy.


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