The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Jun. 20, 2013
Applicant:
Synapse B.v., Maastricht, NL;
Inventors:
Bas H. De Laat, Maastricht, NL;
Hendrik Coenraad Hemker, Maastricht, NL;
Leonie Pelkmans, Maastricht, NL;
Hilde Kelchtermans, Meeuwen-Gruitrode, BE;
Assignee:
SYNAPSE B.V., Maastricht, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/56 (2006.01); G01N 11/14 (2006.01); G01N 33/49 (2006.01); G01N 33/86 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/56 (2013.01); G01N 11/14 (2013.01); G01N 33/4905 (2013.01); G01N 33/582 (2013.01); G01N 33/86 (2013.01); G01N 2333/974 (2013.01);
Abstract
A method for the simultaneous measurement of proteolylic enzyme generation and clot strength in plasma or whole blood or any appropriate biological sample derived from blood. The measurement method encompasses the use of a detectable substrate which includes a moiety that can be released upon reaction with the targeted proteolytic enzyme, and elements for measurement of an increase in viscosity of clot strength.