The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2016

Filed:

Sep. 06, 2014
Applicant:

Cargill Incorporated, Wayzata, MN (US);

Inventors:

Pim Van Hoek, Minnetonka, MN (US);

Aristos Aristidou, Maple Grove, MN (US);

Brian J. Rush, Minneapolis, MN (US);

Assignee:

Cargill Incorporated, Wayzata, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12P 7/56 (2006.01); C12N 1/16 (2006.01); C12N 9/04 (2006.01); C12N 15/81 (2006.01); C12P 7/62 (2006.01); C12Q 1/02 (2006.01);
U.S. Cl.
CPC ...
C12P 7/56 (2013.01); C12N 1/16 (2013.01); C12N 9/0006 (2013.01); C12N 15/815 (2013.01); C12P 7/625 (2013.01); C12Q 1/02 (2013.01); G01N 2333/39 (2013.01); Y02P 20/52 (2015.11);
Abstract

Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.


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