The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2016

Filed:

Oct. 03, 2015
Applicant:

Korea Advanced Institute of Science and Technology, Daejeon, KR;

Inventors:

Sang Yup Lee, Daejeon, KR;

Sung Won Lim, Seoul, KR;

Hyohak Song, Daejeon, KR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/46 (2006.01); C12N 1/20 (2006.01); C12N 15/90 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12P 7/46 (2013.01); C12N 1/20 (2013.01); C12N 9/0006 (2013.01); C12N 9/1029 (2013.01); C12N 9/1217 (2013.01); C12N 15/902 (2013.01); C12Y 203/01054 (2013.01); Y02P 20/52 (2015.11);
Abstract

The present invention relates to a mutant microorganism, which is selected from the group consisting of genus, genusand genus, producing homo-succinic acid and a method for producing homo-succinic acid using the same, and more particularly to a mutant microorganism producing succinic acid at a high concentration while producing little or no other organic acids in anaerobic conditions, which is obtained by disrupting a gene encoding lactate dehydrogenase (ldhA), a gene encoding phosphotransacetylase (pta), and a gene encoding acetate kinase (ackA), without disrupting a gene encoding pyruvate formate lyase (pfl), as well as a method for producing succinic acid using the same. The inventive mutant microorganism has the property of having a high growth rate and succinic acid productivity while producing little or no organic acids, as compared to the prior strains producing succinic acid. Thus, the inventive mutant microorganism is useful to produce succinic acid for industrial use.


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