The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Nov. 24, 2011
Applicants:
Tetsushi Taguchi, Tsukuba, JP;
Makoto Sasaki, Tsukuba, JP;
Yasuyuki Katada, Tsukuba, JP;
Inventors:
Assignee:
National Institute for Materials Science, Ibaraki, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 17/14 (2006.01); A61F 2/82 (2013.01); A61L 31/02 (2006.01); A61L 31/16 (2006.01);
U.S. Cl.
CPC ...
C07K 17/14 (2013.01); A61F 2/82 (2013.01); A61L 31/022 (2013.01); A61L 31/16 (2013.01); A61L 2300/414 (2013.01); A61L 2300/426 (2013.01);
Abstract
Provided is a bio-hybrid material that does not cause elution of nickel ions and has an excellent endothelialization ability, a production method therefor, and a stent. The bio-hybrid material () used includes an alloy part () free of Ni, an organic acid () having two or more active esters, and a cytokine (). The alloy part () free of Ni forms an ester bond with the organic acid (), and the organic acid () and the cytokine () are immobilized via an amide bond.