The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Jun. 21, 2012
Applicants:
Makoto Kakitani, Tokyo, JP;
Kengo Yamawaki, Tokyo, JP;
Inventors:
Makoto Kakitani, Tokyo, JP;
Kengo Yamawaki, Tokyo, JP;
Assignee:
KYOWA HAKKO KIRIN CO., LTD, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/00 (2006.01); C12N 15/62 (2006.01); C07K 14/435 (2006.01); C07K 14/71 (2006.01); A61K 31/711 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/435 (2013.01); A61K 31/711 (2013.01); C07K 14/71 (2013.01); A61K 38/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention provides a protein comprising a truncated form of an extracellular region protein of Frizzled 2, which has higher secretion activity than that of a known protein comprising an extralellular cysteine-rich domain of Frizzled 2 in a production cell and bone mass-increasing activity higher than or equal to that of the known protein, or DNA encoding said protein.