The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2016

Filed:

Sep. 13, 2013
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

The Chancellor, Masters and Scholars of the University of Oxford, Oxford, GB;

Inventors:

Frances Mary Platt, Oxford, GB;

Emyr Lloyd-Evans, Oxford, GB;

Forbes Dennison Porter, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/45 (2006.01); A61K 31/7008 (2006.01); C07D 211/46 (2006.01); A61K 31/513 (2006.01); C07J 43/00 (2006.01); C07D 211/94 (2006.01); A61K 31/7072 (2006.01); A61K 31/661 (2006.01); A61K 31/575 (2006.01); C07D 473/16 (2006.01); A61K 31/708 (2006.01); C07J 7/00 (2006.01); C07H 19/20 (2006.01); A61K 31/6615 (2006.01); A61K 31/197 (2006.01); C07H 19/06 (2006.01); A61K 31/675 (2006.01); A61K 31/445 (2006.01); A61K 31/40 (2006.01); A61K 31/5375 (2006.01); A61K 31/7012 (2006.01); A61K 31/685 (2006.01); A61K 31/42 (2006.01); A61K 31/58 (2006.01); A61K 31/431 (2006.01); A61K 31/52 (2006.01); A61K 31/195 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); A61K 31/195 (2013.01); A61K 31/197 (2013.01); A61K 31/40 (2013.01); A61K 31/42 (2013.01); A61K 31/431 (2013.01); A61K 31/445 (2013.01); A61K 31/513 (2013.01); A61K 31/52 (2013.01); A61K 31/5375 (2013.01); A61K 31/575 (2013.01); A61K 31/58 (2013.01); A61K 31/661 (2013.01); A61K 31/6615 (2013.01); A61K 31/675 (2013.01); A61K 31/685 (2013.01); A61K 31/708 (2013.01); A61K 31/7008 (2013.01); A61K 31/7012 (2013.01); A61K 31/7072 (2013.01); C07D 211/94 (2013.01); C07D 473/16 (2013.01); C07H 19/06 (2013.01); C07H 19/20 (2013.01); C07J 7/009 (2013.01);
Abstract

The present invention provides a compound which is an inhibitor of sphingolipid biosynthesis for use in the treatment of a disease which has a secondary Niemann-Pick type C disease like cellular phenotype.


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