The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Jan. 21, 2014
Applicant:
Zoetis Belgium SA, Louvain-la-Neuve, BE;
Inventors:
Grayson B. Lipford, Watertown, MA (US);
Stefan Bauer, Marburg-Michelbach, DE;
Hermann Wagner, Eching, DE;
Assignee:
Zoetis Belgium SA, Louvain-la-Neuve, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/00 (2006.01); A61K 39/00 (2006.01); A61K 9/127 (2006.01); A61K 47/00 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C07H 21/02 (2006.01); A61K 31/205 (2006.01); A61K 31/7105 (2006.01); A61K 31/7115 (2006.01); A61K 31/712 (2006.01); A61K 31/7125 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C12N 15/117 (2010.01); G01N 33/566 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); A61K 31/205 (2013.01); A61K 31/712 (2013.01); A61K 31/7105 (2013.01); A61K 31/7115 (2013.01); A61K 31/7125 (2013.01); A61K 39/39 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); C12N 15/117 (2013.01); G01N 33/566 (2013.01); A61K 2039/55555 (2013.01); C12N 2310/17 (2013.01);
Abstract
Compositions and methods relating to immunostimulatory RNA oligomers are provided. The immunostimulatory RNA molecules are believed to represent natural ligands of one or more Toll-like receptors, including Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8). The compositions and methods are useful for stimulating immune activation. Methods useful for screening candidate immunostimulatory compounds are also provided.