The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
May. 27, 2013
Fondazione Istituto Italiano Di Technologia, Genoa, IT;
The Regents of the University of California, Oakland, CA (US);
Universita'degli Studi Di Parma, Parma, IT;
Daniele Piomelli, Irvine, CA (US);
Natalia Realini, Valmorea, IT;
Marco Mor, Ghedi, IT;
Chiara Pagliuca, Arezzo, IT;
Daniela Pizzirani, Genoa, IT;
Rita Scarpelli, Rome, IT;
Tiziano Bandiera, Gambolo, IT;
Fondazione Istituto Italiano Di Technologia, Genoa, IT;
Abstract
The present invention concerns, in a first aspect, compounds of Formula I as defined herein, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing such compounds. The present invention also relates to compounds of Formula I for use as acid ceramidase inhibitors, and in the treatment of cancer and other disorders in which modulation of the levels of ceramide is clinically relevant.