The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Aug. 04, 2014
Applicant:
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Inventors:
Helen H. Lu, New York, NY (US);
Jeffrey Spalazzi, Staten Island, NY (US);
Kathie Kionisio, N. Andover, MA (US);
Assignee:
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, New York, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/46 (2006.01); A61L 27/38 (2006.01); A61L 27/44 (2006.01); A61L 27/12 (2006.01); A61F 2/08 (2006.01); A61F 2/30 (2006.01); A61F 2/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/46 (2013.01); A61L 27/12 (2013.01); A61L 27/3839 (2013.01); A61L 27/3891 (2013.01); A61L 27/446 (2013.01); A61F 2/08 (2013.01); A61F 2/0811 (2013.01); A61F 2/3094 (2013.01); A61F 2002/0086 (2013.01); A61F 2002/30004 (2013.01); A61F 2002/30011 (2013.01); A61F 2002/30028 (2013.01); A61F 2002/30029 (2013.01); A61F 2002/30059 (2013.01); A61F 2002/30062 (2013.01); A61F 2002/3093 (2013.01); A61F 2002/30327 (2013.01); A61F 2002/30677 (2013.01); A61F 2002/30968 (2013.01); A61F 2210/0004 (2013.01); A61F 2240/001 (2013.01); A61F 2250/0014 (2013.01); A61F 2250/0023 (2013.01); A61F 2250/0039 (2013.01); A61F 2250/0051 (2013.01); A61F 2250/0067 (2013.01); A61F 2310/00293 (2013.01); A61L 2430/30 (2013.01); A61L 2430/34 (2013.01);
Abstract
Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.