The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Apr. 06, 2015
Silvia S. Jurisson, Columbia, MO (US);
Cathy S. Cutler, Columbia, MO (US);
Anthony J. Degraffenreid, Columbia, MO (US);
Silvia S. Jurisson, Columbia, MO (US);
Cathy S. Cutler, Columbia, MO (US);
Anthony J. Degraffenreid, Columbia, MO (US);
THE CURATORS OF THE UNIVERSITY OF MISSOURI, Columbia, MO (US);
Abstract
The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of radioisotopes present in low concentrations. In certain embodiments, the complex contains a linking domain configured to conjugate the radioisotope trithiol complex to a targeting vector. The invention is also directed to a novel method of linking the radioisotope to a trithiol compound to form the radioisotope trithiol complex. The inventive radioisotope trithiol complexes may be utilized for a variety of applications, including diagnostics and/or treatment in nuclear medicine.