The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Apr. 10, 2015
Applicant:
Medimmune Llc, Gaithersburg, MD (US);
Inventors:
Lakshmaiah Gingipalli, Waltham, MA (US);
Dorin Toader, Gaithersburg, MD (US);
Fengjiang Wang, Waltham, MA (US);
Assignee:
MedImmune LLC, Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/07 (2006.01); A61K 47/48 (2006.01); C07K 5/033 (2006.01); A61K 38/05 (2006.01); C07K 5/02 (2006.01); C07K 5/062 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48415 (2013.01); A61K 38/05 (2013.01); A61K 38/07 (2013.01); A61K 47/48384 (2013.01); A61K 47/48569 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07K 5/02 (2013.01); C07K 5/021 (2013.01); C07K 5/06034 (2013.01);
Abstract
Novel tubulysin derivatives which may be useful as cytotoxic agents to provide therapeutic benefits in the treatment of various types of cancers, alone, as drug conjugates or in combination with other chemotherapies are provided.