The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2016
Filed:
Jan. 21, 2014
Applicant:
Hoffmann-la Roche Inc., Nutley, NJ (US);
Inventors:
Steve Lomuscio, Union, NJ (US);
Hua Ma, Wayne, NJ (US);
Michael Allen Matchett, Montville, NJ (US);
Harpreet K. Sandhu, West Orange, NJ (US);
Navnit Hargovindas Shah, Clifton, NJ (US);
Yu-E Zhang, Wayne, NJ (US);
Assignee:
HOFFMANN-LA ROCHE INC., Nutley, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 9/10 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 47/38 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61K 9/10 (2013.01); A61K 9/146 (2013.01); A61K 9/1641 (2013.01); A61K 9/2054 (2013.01); A61K 9/2027 (2013.01); A61K 47/38 (2013.01);
Abstract
The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.