The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2016

Filed:

Jun. 26, 2009
Applicants:

Quentin Andrew Pankhurst, London, GB;

Eleanor Phoebe Jane Stride, London, GB;

Colin David Porter, London, GB;

Ana García Prieto, London, GB;

Inventors:
Assignee:

UCL Business PLC, London, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 49/22 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0009 (2013.01); A61K 9/5094 (2013.01); A61K 49/223 (2013.01);
Abstract

The invention provides a method of preparing a suspension of microbubbles for use in a carrier liquid, wherein the microbubbles have a gas core and a liquid shell, said liquid shell comprising magnetic nanoparticles, and wherein the microbubbles satisfy the following conditions: (i) the force due to buoyancy (F) of the microbubble in the carrier liquid is greater than the weight (W) of the microbubble; (ii) the magnetic force (F) on the microbubble due to a magnetic field applied to the carrier liquid is greater than the combined weight (W) and force due to buoyancy (F) of the microbubble; (iii) said magnetic force (F) on the microbubble is greater than the force due to viscous drag (F) on the microbubble due to flow of the carrier liquid; and (iv) the scattering cross section (σ) of the microbubble to ultrasound allows the microbubble to be detectable and rupturable on exposure to ultrasound.


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