The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2016

Filed:

Dec. 20, 2012
Applicants:

National University of Singapore, Singapore, SG;

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Young-Tae Chang, Singapore, SG;

Sung Chan Lee, Singapore, SG;

Nam-Young Kang, Singapore, SG;

Seong Wook Yun, Singapore, SG;

Cheryl Kit Mun Leong, Singapore, SG;

Hyung Ho Ha, Singapore, SG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07F 5/02 (2006.01); G01N 33/569 (2006.01); G01N 33/58 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5306 (2013.01); A61K 49/006 (2013.01); A61K 49/0021 (2013.01); C07F 5/02 (2013.01); C07F 5/022 (2013.01); G01N 33/56966 (2013.01); G01N 33/582 (2013.01); G01N 2458/00 (2013.01);
Abstract

The present invention is directed to a fluorescence compound represented by structural Formula (I), with specificity to neural stem cells: (I), or a pharmaceutically acceptable salt thereof. The variables for structural Formula (I) are defined herein. Also described are methods for detection of beta cells, pancreatic islets and microglia cells, comprising using a compound of structural Formula (I) or pharmaceutically acceptable salts thereof. Compounds of structural Formula (I) can also differentiate healthy pancreatic islet cells from diabetic pancreatic islet cells.


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