The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2016

Filed:

Mar. 04, 2014
Applicant:

Christopher Gordon Atwood, San Diego, CA (US);

Inventor:

Christopher Gordon Atwood, San Diego, CA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 21/00 (2006.01); G01N 27/447 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/58 (2006.01); G01N 33/68 (2006.01); G01N 33/52 (2006.01); G01N 33/558 (2006.01);
U.S. Cl.
CPC ...
G01N 27/44721 (2013.01); G01N 33/521 (2013.01); G01N 33/5308 (2013.01); G01N 33/5436 (2013.01); G01N 33/5438 (2013.01); G01N 33/54313 (2013.01); G01N 33/558 (2013.01); G01N 33/582 (2013.01); G01N 33/6848 (2013.01);
Abstract

Methods for the detection of biologically relevant molecules that comprise concentrating such molecules into microscopic holes in a sheet of chemically inert material, restricting the openings, and measuring the electric current through the holes or the fluorescence near the hole openings. The electric current or fluorescence will change as the molecules diffuse out of the holes, providing a measure of the diffusion rate and thereby detecting the presence and characteristics of the molecules. For molecules that interact, the diffusion rate will be slower than for molecules that do not interact, yielding a determination of the molecular interaction. Capping the population of holes and inserting into a mass spectrometer allows identification of the molecules.


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