The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Apr. 15, 2015
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Wai-Yee Leung, San Ramon, CA (US);
Ching-Ying Cheung, San Ramon, CA (US);
Stephen Yue, Eugene, OR (US);
Assignee:
Life Technologies Corporation, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/00 (2006.01); G01N 1/30 (2006.01); A61K 41/00 (2006.01); C07C 66/02 (2006.01); C07D 209/08 (2006.01); C07D 209/12 (2006.01); C07D 209/14 (2006.01); C07D 209/16 (2006.01); C07D 209/18 (2006.01); C07D 209/24 (2006.01); C07D 209/54 (2006.01); C07D 209/60 (2006.01); C07D 209/96 (2006.01); C07D 401/04 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01); C07K 1/13 (2006.01); C09B 23/02 (2006.01); C40B 70/00 (2006.01); G01N 33/533 (2006.01); G01N 33/58 (2006.01); C09B 23/06 (2006.01); C09B 23/08 (2006.01); C09B 23/10 (2006.01); C12Q 1/68 (2006.01); G01N 33/535 (2006.01); G01N 31/22 (2006.01);
U.S. Cl.
CPC ...
G01N 1/30 (2013.01); A61K 41/0057 (2013.01); C07C 66/02 (2013.01); C07D 209/08 (2013.01); C07D 209/12 (2013.01); C07D 209/14 (2013.01); C07D 209/16 (2013.01); C07D 209/18 (2013.01); C07D 209/24 (2013.01); C07D 209/54 (2013.01); C07D 209/60 (2013.01); C07D 209/96 (2013.01); C07D 401/04 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01); C07K 1/13 (2013.01); C09B 23/02 (2013.01); C09B 23/06 (2013.01); C09B 23/083 (2013.01); C09B 23/107 (2013.01); C12Q 1/6825 (2013.01); C40B 70/00 (2013.01); G01N 33/533 (2013.01); G01N 33/535 (2013.01); G01N 33/58 (2013.01); G01N 33/581 (2013.01); G01N 33/582 (2013.01); G01N 31/22 (2013.01); G01N 2001/302 (2013.01); Y10T 436/143333 (2015.01);
Abstract
Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.