The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2016

Filed:

Mar. 13, 2013
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Amy Rowat, Santa Monica, CA (US);

David J. Hoelzle, South Bend, IN (US);

Clara Chan, Los Angeles, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); G01B 7/16 (2006.01); G01N 29/02 (2006.01); G01N 29/036 (2006.01); G01N 29/22 (2006.01); B01L 3/00 (2006.01); C12M 1/00 (2006.01); G01L 1/14 (2006.01); G01N 27/22 (2006.01);
U.S. Cl.
CPC ...
G01B 7/22 (2013.01); B01L 3/5027 (2013.01); C12M 47/04 (2013.01); G01L 1/14 (2013.01); G01N 27/22 (2013.01); G01N 29/022 (2013.01); G01N 29/036 (2013.01); G01N 29/222 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0877 (2013.01); B01L 2400/0487 (2013.01); G01N 2291/02466 (2013.01); G01N 2291/02827 (2013.01);
Abstract

This invention provides methods and devices for the high-throughput characterization of the mechanical properties of cells or particles. In certain embodiments the devices comprise a microfluidic channel comprising: an oscillating element on a first side of the channel; and a detecting element on a second side of the channel opposite the oscillating element, wherein the detecting element is configured to detect a force transmitted through a cell or microparticle by the oscillating element. In certain embodiments the devices comprise a microfluidic channel comprising an integrated oscillator and sensor element on one first side of the channel, wherein the sensor is configured to detect a force transmitted through a cell or microparticle by the oscillator.


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