The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2016

Filed:

Mar. 15, 2013
Applicant:

Butamax(tm) Advanced Biofuels Llc, Wilmington, DE (US);

Inventors:

Larry Cameron Anthony, Aston, PA (US);

Hongxian He, Wilmington, DE (US);

Lixuan Lisa Huang, Hockessin, DE (US);

Daniel P. Okeefe, Ridley Park, PA (US);

Arthur Leo Kruckeberg, Wilmington, DE (US);

Yougen Li, Pennington, NJ (US);

Lori Ann Maggio-Hall, Wilmington, DE (US);

Jessica McElvain, Wilmington, DE (US);

Mark J. Nelson, Newark, DE (US);

Ranjan Patnaik, Newark, DE (US);

Steven Cary Rothman, Wilmington, DE (US);

Assignee:

Butamax Advanced Biofuels LLC, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/16 (2006.01); C12N 15/81 (2006.01); C12N 9/04 (2006.01); C12P 7/42 (2006.01); C12N 1/38 (2006.01);
U.S. Cl.
CPC ...
C12P 7/16 (2013.01); C12N 1/38 (2013.01); C12N 9/0006 (2013.01); C12N 15/81 (2013.01); C12N 15/815 (2013.01); C12P 7/42 (2013.01); Y02E 50/10 (2013.01); Y02P 20/52 (2015.11);
Abstract

Provided herein are recombinant yeast host cells and methods for their use for production of isobutanol. Yeast host cells provided comprise an isobutanol biosynthetic pathway and at least one of reduced or eliminated aldehyde dehydrogenase activity, reduced or eliminated acetolactate reductase activity; or a heterologous polynucleotide encoding a polypeptide having ketol-acid reductoisomerase activity.


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