The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Dec. 19, 2011
Xun Suo, Beijing, CN;
Xianyong Liu, Beijing, CN;
Huali Su, Beijing, CN;
Xinxin Zhao, Beijing, CN;
Xiaoxi Huang, Beijing, CN;
Xun Suo, Beijing, CN;
Xianyong Liu, Beijing, CN;
Huali Su, Beijing, CN;
Xinxin Zhao, Beijing, CN;
Xiaoxi Huang, Beijing, CN;
Zhonghao Chenguang Research Institute of Chemical Industry Company Limited, Fushun County Zigong, Sichuan, CN;
Abstract
Provided is a porcine CD28 receptor molecule, which is: 1) a protein consisting of an amino acid sequence represented by SEQ ID NO:2, or 2) a protein derived from 1) by substitution, deletion or addition of one or several amino acids in the amino acid sequence represented by SEQ ID NO:2 and having equivalent activity with 1). Further provided is a gene for coding the porcine CD28 receptor, the nucleotide sequence of which is shown as SEQ ID NO:1. When the provided co-stimulating receptor CD28 is expressed specifically and highly in a T cell, the activation, proliferation and cell factor secretion activity of the T cell when stimulated by an antigen can be enhanced, thereby enhancing the acquired immune response of a host and enhancing the immune effect of a vaccine.