The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Aug. 30, 2012
Applicants:
Elizabeth M. Long, Calgary, CA;
Stephen M. Robbins, Calgary, CA;
Paul Kubes, Calgary, CA;
Ela Kolaczkowska, Calgary, CA;
Inventors:
Elizabeth M. Long, Calgary, CA;
Stephen M. Robbins, Calgary, CA;
Paul Kubes, Calgary, CA;
Ela Kolaczkowska, Calgary, CA;
Assignee:
UTI Limited Partnership, Calgary, AB, unknown;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 45/06 (2006.01); A61K 38/10 (2006.01); C07K 14/31 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01); C07K 14/31 (2013.01);
Abstract
The present invention provides modified TLR2 ligands useful for modulating inflammatory responses. In particular, the ligands comprise (a) a fatty acid di- or tri-linoleate and (b) a GM1-binding peptide. The linoleate provides the anti-inflammatory function, while the GM1-binding peptide facilitates endocytosis.