The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Nov. 02, 2011
Applicants:
Roberto Falkenstein, Munich, DE;
Thorsten Lemm, Kochel am See, DE;
Markus Strasser, Penzberg, DE;
Hidenari Yamada, Tokyo, JP;
Inventors:
Roberto Falkenstein, Munich, DE;
Thorsten Lemm, Kochel am See, DE;
Markus Strasser, Penzberg, DE;
Hidenari Yamada, Tokyo, JP;
Assignee:
Hoffmann-La Roche Inc., Nutley, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/18 (2006.01); C07K 1/16 (2006.01); C07K 16/06 (2006.01);
U.S. Cl.
CPC ...
C07K 1/18 (2013.01); C07K 16/065 (2013.01);
Abstract
Herein is reported a method for the purification of an antibody directly captured from clarified cell culture supernatants using Streamline CST and/or Capto MMC, wherein especially product related (aggregates and fragments) and process related impurities (host cell protein, media components) could efficiently be removed, resulting in a preparation with a purity comparable to classical protein A affinity chromatography.