The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Jan. 30, 2009
Applicants:
Sang Jin Lee, Winston-Salem, NC (US);
James J. Yoo, Winston-Salem, NC (US);
Anthony Atala, Winston-Salem, NC (US);
Inventors:
Sang Jin Lee, Winston-Salem, NC (US);
James J. Yoo, Winston-Salem, NC (US);
Anthony Atala, Winston-Salem, NC (US);
Assignee:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/08 (2006.01); A61L 27/48 (2006.01); A61L 27/26 (2006.01); A61L 27/38 (2006.01); A61L 27/58 (2006.01);
U.S. Cl.
CPC ...
A61L 27/48 (2013.01); A61L 27/26 (2013.01); A61L 27/3826 (2013.01); A61L 27/3873 (2013.01); A61L 27/58 (2013.01); A61L 2430/30 (2013.01);
Abstract
Provided herein are anisotropic muscle implants that have a biodegradable scaffold comprising a plurality of fibers oriented along a longitudinal axis. The implants may include mammalian muscle cells seeded and/or fused into myotubes on the scaffold. Methods of forming the muscle implants are provided, as are methods of treating a subject in need of skeletal muscle reconstruction.