The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2016

Filed:

Aug. 20, 2008
Applicants:

Sonya Shortkroff, Braintree, MA (US);

Joseph Khoury, Dedham, MA (US);

Laurence J. B. Tarrant, Northampton, MA (US);

Hans P. I. Claesson, Wayland, MA (US);

Robert Lane Smith, Palo Alto, CA (US);

Inventors:

Sonya Shortkroff, Braintree, MA (US);

Joseph Khoury, Dedham, MA (US);

Laurence J. B. Tarrant, Northampton, MA (US);

Hans P. I. Claesson, Wayland, MA (US);

Robert Lane Smith, Palo Alto, CA (US);

Assignee:

Histogenics Corporation, Waltham, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/02 (2006.01); A61B 17/08 (2006.01); A61L 27/38 (2006.01); A61L 27/24 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3839 (2013.01); A61L 27/24 (2013.01); A61L 27/3804 (2013.01); A61L 27/56 (2013.01);
Abstract

A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.


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