The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Dec. 04, 2013
Fujian South Pharmaceutical Co., Ltd, Sanming, Fujian, CN;
Huaxing Zhan, Shanghai, CN;
Zhihong Jiang, Macao, CN;
Dan Wang, Shanghai, CN;
Xin Shen, Shanghai, CN;
Jidong Yang, Shanghai, CN;
Jianping Luo, Fujian, CN;
Hongsheng Zhang, Yunnan, CN;
Min Du, Fujian, CN;
Pengfei Miao, Shanghai, CN;
FUJIAN SOUTH PHARMACEUTICAL CO., LTD., Fujian, CN;
Abstract
A saponin nano micelle, preparing method, application and pharmaceutical composition thereof is disclosed in the present invention. The saponin nano micelle comprises one or more of saponins represented by formula 1, in which, Rand Rare independently —H or a hydrophilic group, Ris —H or —OH, Ris a lipophilic group. The preparing method of the saponin nano micelle is that mixing the saponin with an organic solvent which can dissolve saponin, and then removing the organic solvent. The saponin micelle acts as a convey medium of the drug ingredients, and can replace conventional drug carriers such as pharmaceutical solubilizers or polymeric micelle, which has high safety and great significance. The pharmaceutical ingredients can prolong circulation time and biological half-life of drug in the blood, and increase the accumulation of drug in lesions, and reduce adverse reactions.