The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Jan. 16, 2015
Applicant:
Enzo Therapeutics, Inc., Farmingdale, NY (US);
Inventors:
Yaron Ilan, Givat Massua, IL;
Eran Elinav, Ramat Beit Hakerem, IL;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 38/22 (2006.01); A61K 38/02 (2006.01); A61K 38/16 (2006.01); A61K 45/06 (2006.01); A61N 5/10 (2006.01); C07K 16/26 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/3955 (2013.01); A61K 38/02 (2013.01); A61K 38/16 (2013.01); A61K 38/22 (2013.01); A61K 38/2264 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07K 16/26 (2013.01); A61K 2039/505 (2013.01); C07K 2317/30 (2013.01);
Abstract
The present invention is directed to methods for modulating the Th/Th2 cell balance toward anti-inflammatory cytokine producing cells in a subject comprising decreasing the amount, the expression, or the activity of leptin in a subject sufficient to modulate the Th1/Th2 cell balance toward anti-inflammatory cytokine producing cells. The invention is also directed to methods of treatment of an immune-related disorder in a subject comprising decreasing the amount, the expression, or the activity of leptin in the subject sufficient to treat the immune-related disorder.