The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Apr. 04, 2011
Dae Jin Kim, Hwaseong-si, KR;
Min Young Kim, Suwon-si, KR;
Jin Sun Kim, Yongin-si, KR;
Sung Hee Hong, Suwon-si, KR;
Sung Youb Jung, Suwon-si, KR;
SE Chang Kwon, Seoul, KR;
Dae Jin Kim, Hwaseong-si, KR;
Min Young Kim, Suwon-si, KR;
Jin Sun Kim, Yongin-si, KR;
Sung Hee Hong, Suwon-si, KR;
Sung Youb Jung, Suwon-si, KR;
Se Chang Kwon, Seoul, KR;
HANMI SCIENCE CO., LTD, Hwaseong-si, KR;
Abstract
The present invention relates to a long-acting interferon beta formulation having improved in vivo duration and stability, comprising an interferon beta conjugate that is prepared by covalently linking interferon beta with an immunoglobulin Fc region via a non-peptidyl polymer, and a preparation method thereof. The long-acting interferon beta formulation of the present invention maintains in vivo activity of interferon beta at a relatively high level and remarkably increases the serum half-life thereof, thereby being used for various diseases, for which interferon is efficacious.