The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Sep. 08, 2011
Yair Reisner, Old Jaffa, IL;
Assaf Lask, Rehovot, IL;
Eran Ophir, Rehovot, IL;
Noga Or-geva, Rehovot, IL;
Adva Cohen, Rehovot, IL;
Ran Afik, Rehovot, IL;
Esther Bachar-lustig, Rehovot, IL;
Yaki Eidelstein, Rehovot, IL;
Yair Reisner, Old Jaffa, IL;
Assaf Lask, Rehovot, IL;
Eran Ophir, Rehovot, IL;
Noga Or-Geva, Rehovot, IL;
Adva Cohen, Rehovot, IL;
Ran Afik, Rehovot, IL;
Esther Bachar-Lustig, Rehovot, IL;
Yaki Eidelstein, Rehovot, IL;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Abstract
A method of treating a disease in a subject in need thereof is disclosed. The method comprising: (a) transplanting a non-syngeneic cell or tissue graft to the subject; and (b) administering to the subject a therapeutically effective amount of an isolated population of cells comprising non-graft versus host (GVHD) inducing anti-third party cells having a central memory T-lymphocyte (Tcm) phenotype, the cells being tolerance-inducing cells and capable of homing to the lymph nodes following transplantation, and further wherein the cells are either: (i) non-syngeneic with both the subject and the graft; or (ii) non-syngeneic with the graft and syngeneic with the subject, thereby treating the subject.