The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2016

Filed:

Sep. 20, 2012
Applicant:

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Jerusalem, IL;

Inventors:

Simon Benita, Tel Aviv, IL;

Orit Amsalem, Jerusalem, IL;

Taher Nassar, Kfar Turaan, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 9/51 (2006.01); A61K 31/713 (2006.01); A61K 47/48 (2006.01); C12N 15/88 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/5153 (2013.01); A61K 9/0019 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 9/5146 (2013.01); A61K 9/5169 (2013.01); A61K 9/5192 (2013.01); A61K 31/713 (2013.01); A61K 47/48869 (2013.01); C12N 15/1138 (2013.01); C12N 15/88 (2013.01); C12N 2310/14 (2013.01); C12N 2320/52 (2013.01); C12N 2810/859 (2013.01);
Abstract

The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either hydrophobic or hydrophilic, from stable nanoparticles of opposite characteristics. The protection of the active agent was achieved by loading the agent to be protected, into nanocarriers, which were subsequently encapsulated into sub-micron nanoparticles. The sub-micron nanoparticles formation has been successfully achieved by the use of novel nano spray techniques.


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