The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2016
Filed:
Dec. 05, 2012
Applicant:
X-body, Inc., Waltham, MA (US);
Inventors:
Yan Chen, Lexington, MA (US);
Richard W. Wagner, Cambridge, MA (US);
Csaba Pazmany, Cambridge, MA (US);
Assignee:
X-Body, Inc., Waltham, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); C07K 16/22 (2006.01); C07K 14/49 (2006.01); C07K 14/71 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); C07K 14/49 (2013.01); C07K 14/71 (2013.01); C07K 16/2863 (2013.01); A61K 39/00 (2013.01); C07K 16/28 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present invention provides binding polypeptides (e.g., antibodies or fragments thereof) that specifically bind to a target antigen (e.g., a human antigen, e.g., human PDGFRβ) with high affinity. The invention also provides, libraries of binding polypeptides, pharmaceutical compositions, as well as nucleic acids encoding binding polypeptides, recombinant expression vectors and host cells for making such binding polypeptides. Methods of using binding polypeptide of the invention to diagnose and treat disease are also encompassed by the invention.