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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9416163 B1

PDFFull Text
Date of Patent:
Aug. 16, 2016

Filed:

Mar. 17, 2010

Synthetic oligopeptides designed from mite cysteine proteases and methods for the production of polyclonal igy antibodies for the detection of intradomiciliary mites

Applicants:

Luis Alejandro Barrera, Puerto, CO;

Eduardo Egea, Puerto, CO;

Johana Espejo, Puerto, CO;

Catalina Sosa, Puerto, CO;

Elkin Navarro, Puerto, CO;

Gloria Garavito, Barranquilla, CO;

Dary Luz Mendoza, Barranquilla, CO;

Leonardo Lareo, Puerto, CO;

Luis Miguel Renjifo Martinez, Bogotá, CO;

Inventors:

Luis Alejandro Barrera, Puerto, CO;

Eduardo Egea, Puerto, CO;

Johana Espejo, Puerto, CO;

Catalina Sosa, Puerto, CO;

Elkin Navarro, Puerto, CO;

Gloria Garavito, Barranquilla, CO;

Dary Luz Mendoza, Barranquilla, CO;

Leonardo Lareo, Puerto, CO;

Assignees:

FUNDACION UNIVERSIDAD DEL NORTE, Barranquilla, CO;

PONTIFICIA UNIVERSIDAD JAVERIANA, Bogota, CO;

Attorney:

Drinker Biddle & Reath LLP

Primary Examiner:

Nora Rooney

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/04 (2006.01); A61K 39/00 (2006.01); A61K 39/35 (2006.01); A61K 39/36 (2006.01); A61K 39/395 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43531 (2013.01); A61K 39/35 (2013.01); A61K 38/00 (2013.01); A61K 2039/55516 (2013.01);
Abstract

The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the speciesand, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.

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