The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2016
Filed:
Jul. 10, 2012
5'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
Vishal A. Verma, Jersey City, NJ (US);
Ashok Arasappan, Bridgewater, NJ (US);
F. George Njoroge, Carmel, IN (US);
Vinay Girijavallabhan, Denville, NJ (US);
Stephane L. Bogen, Somerset, NJ (US);
Qun Dang, Westfield, NJ (US);
David B. Olsen, Lansdale, PA (US);
Vishal A. Verma, Jersey City, NJ (US);
Ashok Arasappan, Bridgewater, NJ (US);
F. George Njoroge, Carmel, IN (US);
Vinay Girijavallabhan, Denville, NJ (US);
Stephane L. Bogen, Somerset, NJ (US);
Qun Dang, Westfield, NJ (US);
David B. Olsen, Lansdale, PA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention relates to 5'-Substituted Nucleoside Derivatives of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein X, Y, Z, R, Rand Rare as defined herein and B is a 7-deaza-9-purinyl moiety. The present invention also relates to compositions comprising at least one 5′-Substituted Nucleoside Derivative, and methods of using the 5′-Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.